Cyanotic Congenital Heart Lesions

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Cyanosis is caused by lesions that lead to right-to-left shunting of blood, in which blood coming from the right ventricle bypasses lungs to various degrees before entering systemic circulation.
These lesions can be remembered as the 5 Ts:
1. Tetralogy of Fallot (most common cause of early cyanosis)
2. Transposition of the great vessels
3. Truncus arteriosus
4. Total anomalous pulmonary venous return
5. Tricuspid atresia

Squatting increases left-sided pressure or systemic vascular resistance (SVR) by compression of femoral arteries; this can make SVR higher than PVR (pulmonary vascular resistance, or right-sided pressure) and thus may decrease right-to-left shunting and allow more blood to pass through the pulmonary circulation before entering the systemic circulation, alleviating symptoms of cyanosis.

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Hello! I am Dukagjin Zeqiraj from Kosovo. I have finished Medical Faculty in Prishtina ( capital city of Kosovo). Now I live in Pristina and I work in QKMF Podujeve (family medicine center). Tel: +38344311154